Anal Squamous Cell Carcinoma (ASCC) is an uncommon cancer with an incidence rate between 1 and 2 per 100,000 per year.

However, the incidence of ASCC is increasing rapidly, with an overall 63% increase in incidence rate of ASCC in the UK since the 1990’s.

Unfortunately, there is much discrepancy in the best surgical practice for the treatment and prevention of ASCC, regional guidelines differ considerably and there is widespread variance in practice between different clinical centers.

As ASCC is a rare cancer, so far it has been difficult do any research in the cause of the increasing incidence or best treatment and prevention of ASCC.

The mASCARA study team have developed a research registry for patients with ASCC and its precursor Anal Intraepithelial Neoplasia.

We hope by collaborating internationally with other clinical centers we can be able to start answering the unanswered questions.

mASCARA is a secure web-based platform that has been designed to be GDPR compliant and has gained ethical approval from a specialist GDPR database Research and Ethics Committee in the UK.

We are now open to recruitment to clinical centers worldwide, please download the information pack below for more details and visit our contact page to register your interest.